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Benefits of an original booster dose against omicron may be affected by prior SARS-CoV-2 infection

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mRNA COVID-19 vaccines are less effective against omicron infections than other variants. A study published December 1 in the open access journal PLOS Medicine by Margaret L. Lind at the Yale School of Public Health and colleagues suggests that the additional protection offered by the initial booster shot may be reduced among people with a previous COVID-19 infection.

A deep dive into the omicron variant’s origin

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