Innovations

Diabetic status modifies the impact of an NAFLD-associated single nucleotide polymorphism

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Specialist researcher holding microscope slide analyzing blood sample working at coronavirus vaccine development during virus examination in microbiology hospital laboratory. Biochemistry experiment

Context is known to influence many spheres. And now, researchers from Japan have found that a patients’ health context—that is, the other conditions a patient has—can determine whether a specific gene mutation is helpful or harmful. Researchers from Tokyo Medical and Dental University (TMDU) and Cincinnati Children’s Hospital Medical Center (CCHMC) have revealed that a genetic mutation with a controversial connection to liver disease confers different levels of risk depending on whether patients have diabetes.

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