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Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

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A network of molecules and atoms of glass and crystals constitute a single system. 3D illustration

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

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