Innovations

HUSH gene-silencing complex contributes to normal brain development and function

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Research scientist with gloves holding blood sample on glass in laboratory. Biology doctor analyzing plasma dna for medical discovery in pharmaceutical industry. Science equipment on desk

The gene-silencing complex HUSH might be involved in complex disorders affecting the brain and neurons. However, its mechanism of action remains unclear. Researchers from the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) now uncover the in vivo targets and physiological functions of a component of the HUSH gene-silencing complex and one of its associated proteins.

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