Innovations

Immune signaling component FBXC-58 found to mediate dietary restriction effects on healthy aging in C. elegans

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Biochemistry laboratory research, Scientist or medical in lab coat holding test tube with Using Microscope reagent with drop of color liquid over glass equipment working at the laboratory.

Dietary restriction (DR) is a highly effective and reproducible intervention that prolongs longevity in many organisms. The molecular mechanism of action of DR is tightly connected with the immune system; however, the detailed mechanisms and effective downstream factors of immunity that mediate the beneficial effects of DR on aging remain unknown.

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