Innovations

Measuring reduced alcohol consumption, not just abstinence, effective for evaluating medication treatment for drinking

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An analysis of combined pharmacotherapy for reducing drinking and smoking has validated findings that measuring reductions in the amount of drinking, not just abstinence, was an effective outcome for alcohol medication trials. Currently, the Food and Drug Administration, which oversees U.S. clinical trials, accepts total abstinence and percentage of days with no drinking as criteria for success in clinical trials of medication to treat alcohol use disorder.

Study shows limited diversity in psychophysiology trials

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