Innovation in Medicine

Meet the (protein) neighbors: New method lets researchers detect proteins in close proximity in single cells

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Today, most methods to determine the proteins inside a cell rely on a crude census—scientists usually grind a large group of cells up before characterizing their genetic material. But just as a population of 100 single people differs in many ways from a population of 20 five-person households, this kind of description fails to capture information about how proteins are interacting and clumping together into functional groups.

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