Innovation in Medicine

Researchers develop algorithm to identify microbial contaminants in low microbial biomass microbiomes

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One of the major challenges in microbiome science has been distinguishing what is a potential environmental contaminant from a true, bona fide microbiome signal. Challenges associated with metagenomic sequencing with low biomass environments include the distinction between a true signal versus contamination, a remnant DNA from a sampling kit or extraction kit or the environment.

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