Researchers investigate the multi-omic landscape of steatosis-to-NASH progression in mice

Close Up Scientist using microscope in laboratory room while making medical testing and research

The global prevalence of nonalcoholic fatty liver disease (NAFLD) is estimated to be > 25% and will continue to rise. NAFLD comprises a spectrum of liver disorders ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH). While NAFL is generally considered to be a benign condition, NASH is prone to develop into severe end-stage liver diseases. However, the molecular mechanisms of steatosis-to-NASH progression remain poorly understood.

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