Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

3D render of a medical background with DNA strands

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

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