Innovations

Trial demonstrates acute lymphoblastic leukemia treatment advance

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Research scientist with gloves holding blood sample on glass in laboratory. Biology doctor analyzing plasma dna for medical discovery in pharmaceutical industry. Science equipment on desk

Late-breaking research reveals a major treatment advance for adults with newly diagnosed B lineage acute lymphoblastic leukemia (ALL). The randomized phase 3 study E1910 evaluated blinatumomab immunotherapy in patients with a good prognosis after an initial round of chemotherapy. After about 3.5 years of follow-up, 83% of the patients who went on to receive additional standard consolidation chemotherapy plus experimental blinatumomab were alive versus 65% of those who received chemotherapy only.

Effects of antidepressants taken during pregnancy are poorly understood, scientists note

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